Chlamydia trachоmatis IgG - ELISA

General information:

Serological research to prove the causative agent. The tests are of high sensitivity and specificity and with the ability to determine antibodies of different classes. Their advantage is that they are available and their reading is not subjective. Important in serological diagnostics is the dynamics of antibody values, single, even high titers are not always indicative. In urethritis or superficial processes, antibodies may be absent. The results must be interpreted in connection with the history and the course of the disease by the attending physician! In certain cases, additional tests (PCR amplification methods) are required, which you can ask about in the laboratory. Chlamydiae are obligate intracellular microorganisms with complex morphological properties and clinical features. They are widespread, more than 20 clinical syndromes are known - eye diseases, sexually transmitted urogenital infections in both sexes, diseases in newborns. Diseases vary from mild asymptomatic infections to severe lesions of the urogenital tract, especially in women. The latter increase the frequency of abortions, infertility, antenatal mortality.

Types of infections:

• Eye infections-trachoma (chronic keratoconjunctivitis leading to blindness), conjunctivitis with inclusions
• Sexually transmitted urogenital infections in men - urethritis (acute and chronic), postgonococcal urethritis (in co-infection after treatment for gonorrhea), prostatitis, epididymitis, orchiepididymitis and proctitis. These complications occur in 35-50% of men and affect young age 18-45 years. After complications, atrophy of the testicles, obliteration of the epididymis and the seminal canal can develop, which leads to disturbances in fertility (sterility). Co-infections with other microorganisms such as Ureaplasma, Mycoplasma, Trichomonas vaginalis, bacteria.
• Sexually transmitted urogenital infections in women - cervicitis, endocervicitis, vaginitis, bartholinitis, endometritis, salpingitis, parametritis, pelvic inflammatory disease, abortion, stillbirth, inflammation of the placenta. Infections in women are often unrecognized - 50-70% are asymptomatic, tend to chronic course and frequent relapses. In females, there are also co-infections with other causes. Salpingitis (inflammation of the fallopian tubes) is the cause of ectopic pregnancies and sterility.
• Disease Lymphogranuloma venereum
• Joint diseases - reactive arthritis (sexually acquired arthritis at a young age)
• Reiter's syndrome-triad of urethritis, arthritis, conjunctivitis
• Infections in newborns - conjunctivitis, pneumonia (atypical)

Chlamydia trachomatis (Chlamydia trach.) IgA and Chlamydia trachomatis (Chlamydia trach.) IgG are tested

The treatment of C.trachomatis infections is antibiotic and long-term! It is appointed by the relevant specialist!

Sample required:

Venous blood

Key words:

Chlamydia trachomatis IgG ELISA