Coagulation factor 13, Fibrin Stabilizing Factor
General information:
Factor deficiency is inherited autosomally recessively by both parents and men and women suffer equally. The most rare disease due to blood coagulation factors (1: 5,000,000).
The factor stabilizes the formed clot. Without it, the clot will not develop, but will collapse and cause recurrent bleeding. Umbilical cord blood is reported in 80% of cases with a deficiency. Spontaneous brain haemorrhages, high lethality, were observed at 30%. Other symptoms are similar to other deficiency states: sufions, bruises, nasal bleeding, joints, interventions, menorrhagia, abortion, infertility in both sexes.
Patients with this deficiency give normal values in blood clotting tests.
Sample required:
Venous blood in the morning in fasting
Key words:
Coagulation factor, Fibrin Stabilizing Factor